Type 1 diabetes — also referred to as insulin dependent diabetes or juvenile diabetes — affects over 34 million people worldwide, or 1 in 300 children. Diabetes is the leading cause of kidney failure, new cases of adult blindness and non-traumatic lower-limb amputations. Type 1 diabetes accounts for $14.9 billion in healthcare costs in the U.S. each year.
According to the American Academy of Allergy, Asthma & Immunology, in 2009, asthma affects 25 million people in the US and 300 million people worldwide. According to the American Lung Association, the annual direct health care cost of asthma is approximately $50.1 billion; indirect costs (e.g. lost productivity) add another $5.9 billion, for a total of $56.0 billion dollars. Steroid resistant asthma afflicts less than 5% of the total asthma population, but accounts for up to 50% of healthcare spending on asthma.